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Tocris™ NBC 6

Catalog No. 692510
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69-251-0 10 mg
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Catalog No. 69-251-0 Supplier Tocris™ Supplier No. 6925/10
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Description

NLRP3 inflammasome inhibitor

NBC 6 is a NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod (Cat. No. 3700) induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).

Specifications

Chemical Name or Material (T4)-[2-Acetyl-4,4,4-trichloro-3-(imino-κN)butanamidito-κO]diphenylboron
CAS 2068818-02-8
Quantity 10 mg
Target Inflammasomes Inhibitors
Molecular Formula C18H16BCl3N2O2
Formula Weight 1869
Purity 98%
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