NBN Mouse anti-Human, Clone:7E4C2, Abnova™

Catalog No.	Quantity
89-334-476	100 μg

Catalog No. 89-334-476 Supplier Abnova Corporation Supplier No. MAB17791

Description

Mouse monoclonal antibody raised against recombinant human NBN.

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq]

Specifications

• Antigen: NBN
• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 7E4C2
• Conjugate: Unconjugated
• Description: nibrin
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-1:400)
  Immunocytochemistry (1:200-1:1000)
  Immunohistochemistry (1:200-1:1000)
  Western Blot (1:500-1:2000)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: NBN
• Gene Alias: AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 467-615 of human NBN from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 4683
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a