Invitrogen™ NBS1 Monoclonal Antibody (1D7)

Catalog No.	Quantity
MA123265	100 μL

Catalog No. MA123265 Supplier Invitrogen™ Supplier No. MA123265

Description

Mouse Monoclonal Antibody

Predicted molecular weight 91 kDa. Positive control: MCF7, HeLa (NE), Raji.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Specifications

• Antigen: NBS1
• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 1D7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and no preservative; pH 7
• Gene: NBN
• Gene Accession No.: O60934, Q9JIL9, Q9R207
• Gene Alias: AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
• Gene Symbols: NBN
• Host Species: Mouse
• Immunogen: The complete coding region of the human p95/NBS1 expressed in E. coli.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27354, 4683, 85482
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1