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Invitrogen™ NBS1 Polyclonal Antibody
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Catalog No. PIPA522972
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100 μL
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PIPA522972 100 μL
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Catalog No. PIPA522972 Supplier Invitrogen™ Supplier No. PA522972
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Description

Rabbit Polyclonal Antibody

Suggested positive control: antigen standard for NBN (transient overexpression lysate), HeLa whole cell extract.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NBS1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.1% sodium azide
Gene NBN
Gene Accession No. O60934, Q9R207
Gene Alias AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Gene Symbols NBN
Host Species Rabbit
Immunogen Synthetic peptide made to an internal portion of the mouse NBS1 protein (within residues 350-400).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27354, 4683
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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