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NCOA62 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
Specifications
Specifications
| Antigen | NCOA62 |
| Applications | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/ml |
| Conjugate | Unconjugated |
| Formulation | phosphate, tris citrate with 0.09% sodium azide; pH 7-8 |
| Gene | SNW1 |
| Gene Accession No. | Q13573, Q9CSN1 |
| Gene Alias | PPS, SKIP |
| Gene Symbols | Snw1 |
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