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Invitrogen™ NDUFS4 Polyclonal Antibody
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Catalog No. PIPA521677
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PIPA521677 100 μL
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Catalog No. PIPA521677 Supplier Invitrogen™ Supplier No. PA521677
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, mouse brain, rat heart. Predicted reactivity: Mouse (86%), Rat (86%), Zebrafish (80%), Chimpanzee (99%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDUFS4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene NDUFS4
Gene Accession No. O43181, Q5XIF3, Q9CXZ1
Gene Alias 6720411N02Rik; AQDQ; C1-18k; CI-18; CI-18 kDa; CI-AQDQ; complex I 18kDa subunit; complex I-18 kDa; Complex I-AQDQ; mitochondrial respiratory chain complex I (18-KD subunit); NADH dehydrogenase (ubiquinone) Fe-S protein 4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; NADH:ubiquinone oxidoreductase subunit S4; NADH-ubiquinone oxidoreductase 18 kDa subunit; NDUFS4
Gene Symbols NDUFS4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human NDUFS4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17993, 4724, 499529
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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