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Invitrogen™ Nestin Monoclonal Antibody (10C2)
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Catalog No. PIMA1110
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100 μg
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Catalog No. Quantity
PIMA1110 100 μg
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Catalog No. PIMA1110 Supplier Invitrogen™ Supplier No. MA1110
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Description

Mouse Monoclonal Antibody

MA1-110 has been successfully utilized in Western Blot, immunocytochemistry, flow cytometry, and immunofluorescence applications in human samples. MA1-110 also acts a neuronal stem cell marker and detects a band in Western blot at ~250 kDa.

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nestin
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 10C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol, 1mg/mL BSA and 0.05% sodium azide
Gene Nes
Gene Accession No. P48681, Q6P5H2
Gene Alias AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin
Gene Symbols Nes
Host Species Mouse
Immunogen Human nestin protein corresponding to residues 1464-1614.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10763, 18008
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

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