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Invitrogen™ Nestin Polyclonal Antibody

Catalog No. p-7246560
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500 μL
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PIPA5143544 500 μL
PIPA5143578 100 μL
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Catalog No. PIPA5143544 Supplier Invitrogen™ Supplier No. PA5143544
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Description

Chicken Polyclonal Antibody

Nestin Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nestin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Nes
Gene Accession No. P21263, P48681, Q6P5H2
Gene Alias AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin
Gene Symbols Nes
Host Species Chicken
Immunogen Recombinant construct, amino acids 317-630 of the human protein expressed in and purified from E. coli.
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10763, 18008, 25491
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgY
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