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Invitrogen™ NEU1 Polyclonal Antibody
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Catalog No. PIPA592879
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PIPA592879 100 μL
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Catalog No. PIPA592879 Supplier Invitrogen™ Supplier No. PA592879
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PRKGRLIVCG HGTLERDGVF CLLSDDHGAS WRYGSGVSGI PYGQPKQEND FNPDECQPYE LPDGSVVINA RNQNNYHCHC RIVLRSYDAC DTLRPRDVTF DPELVDPVVA AGAVVTSSGI VFFSNPAHPE FRVNLTLRWS FSNGTSWRKE TVQLWPGPSG YSSLATLEGS MDGEEQAPQL YVLYEKGRNH YTESISVAKI SVYGTL Positive Samples: Mouse liver, Rat liver; Cellular Location: Cell membrane, Cytoplasmic vesicle, Lumenal side, Lysosome lumen, Lysosome membrane, Peripheral membrane protein.

NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NEU1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.73 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene NEU1
Gene Accession No. O35657, Q99519, Q99PW3
Gene Alias AA407268; AA407316; Acetylneuraminyl hydrolase; Aglp; Apl; Bat7; Bat-7; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9; G9 sialidase; HLA-B-associated transcript 7; lysosomal sialidase; Map-2; N-acetyl-alpha-neuraminidase 1; NANH; Neu; NEU1; Neu-1; neuraminidase 1; neuraminidase 1 (lysosomal sialidase); SIAL1; sialidase 1; sialidase 1 (lysosomal sialidase); sialidase-1
Gene Symbols NEU1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18010, 24591, 4758
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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