Invitrogen™ NeuroG3 Recombinant Rabbit Monoclonal Antibody (10H35L14)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 703206

Catalog No. 70-320-6

Description

This antibody is predicted to react with Monkey, Pig, Goat, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Neurog 3 protein contains one basic helix-loop-helix (bHLH) domain.It is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Not only does itinitiates endocrine cell differentiation, italso promotes islet cell maturation and maintains islet function. It is reported that Neurogenin 3 can redirect the differentiation of bipotential secretory progenitors to endocrine rather than goblet cell fate.

Specifications

• Antigen: NeuroG3
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P70661, Q9Y4Z2
• Gene Symbols: NEUROG3
• Immunogen: Protein corresponding to human Neurogenin-3 [aa1-aa214].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: 10H35L14
• Conjugate: Unconjugated
• Gene: NEUROG3
• Gene Alias: ATH4B; Atoh5; atonal homolog 5; BHLHA7; Class A basic helix-loop-helix protein 7; helix-loop-helix protein mATH-4B; LOW QUALITY PROTEIN: neurogenin-3; Math4B; Neurog3; neurogenin 3; Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B); neurogenin3; neurogenin-3; ngn3; NGN-3; Protein atonal homolog 5; Relax; transcriptional regulator, Relax
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11925, 50674
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid