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Invitrogen™ NeuroG3 Recombinant Rabbit Monoclonal Antibody (10H35L14)

Catalog No. 703206
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Catalog No. Quantity
70-320-6 100 μg
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Catalog No. 70-320-6 Supplier Invitrogen™ Supplier No. 703206
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Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Pig, Goat, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Neurog 3 protein contains one basic helix-loop-helix (bHLH) domain.It is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Not only does itinitiates endocrine cell differentiation, italso promotes islet cell maturation and maintains islet function. It is reported that Neurogenin 3 can redirect the differentiation of bipotential secretory progenitors to endocrine rather than goblet cell fate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NeuroG3
Applications Western Blot
Classification Recombinant Monoclonal
Clone 10H35L14
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene NEUROG3
Gene Accession No. P70661, Q9Y4Z2
Gene Alias ATH4B; Atoh5; atonal homolog 5; BHLHA7; Class A basic helix-loop-helix protein 7; helix-loop-helix protein mATH-4B; LOW QUALITY PROTEIN: neurogenin-3; Math4B; Neurog3; neurogenin 3; Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B); neurogenin3; neurogenin-3; ngn3; NGN-3; Protein atonal homolog 5; Relax; transcriptional regulator, Relax
Gene Symbols NEUROG3
Host Species Rabbit
Immunogen Protein corresponding to human Neurogenin-3 [aa1-aa214].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11925, 50674
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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