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CPC Scientific H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Val-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH (trifluoroacetate salt) 1MG

Supplier: CPC Scientific NEUP012B

This peptide is a modulator of arousal and possibly anxiety-related behaviour. It acts by activating its cognate receptor (NPSR) and inducing mobilization of intracellular Ca2+. Central administration of NPS induced wakefulness and reduced slow wave and REM sleep in rats. These peptides represent potential lead compounds for the treatment of sleep and anxiety disorders. ONE-LETTER SEQUENCE: SFRNGVGSGNKKTSFRRAKQMOLECULAR FORMULA: C95H160N34O27MOLECULAR WEIGHT:2210.53STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [412938-75-1], RESEARCH AREA: NeuropeptidesREFERENCES: Y.-L.Xu et al., Neuron, 43, 487 (2004); N.Okamura and N.K.Reinscheid, Stress, 10, 221 (2007); K.Domschke et al., Mol. Psychiatry, 16, 938 (2011)
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