Invitrogen™ NF-H Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA110002

Catalog No. 01-670-259

Description

This antibody reacts primarily with the phosphorylated axonal form of NF-H and shows some cross-reactivity with phosphorylated NF-M, which has similar phosphorylation sites to NF-H.

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

Specifications

• Antigen: NF-H
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nefh
• Gene Alias: 200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg
• Host Species: Chicken
• Purification Method: PEG precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 100064328, 100156492, 24587, 380684, 442940, 4744, 528842
• Content And Storage: 4°C
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P12036, P12037, P16884, P19246
• Gene Symbols: Nefh
• Immunogen: Native NF-H purified from bovine spinal cord.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Bovine, Pig, Horse
• Product Type: Antibody
• Isotype: IgY

Safety and Handling

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