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Abcam NF-kappaB Activation Inhibitor VI, Benzoxathiole Compound, Solid, >95% Purity, 25 mg

Catalog No. 502583247
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50-258-3247 25 mg
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Catalog No. 50-258-3247 Supplier Abcam Supplier No. AB14595425MG
May include imposed supplier surcharges.
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Description

Cell-permeable benzoxathiole compound that acts as a potent IKK-2 inhibitor to block NF-κB activation.

  • Purity: >95%
  • Molecular Weight: 273.4 Da
  • Mechanism: Cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor
  • Key Activity: Inhibits LPS-induced NF-κB activation (IC50 = 1.0 μM) and nitrite production (IC50 = 0.7 μM) in RAW 264.7 cells
  • In Vivo Effect: Prevents LPS-induced septic death in mice
  • Physical Form: Solid
  • CAS Number: 113760-29-5

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule IKK-2
Shipping Condition Ambient
Content And Storage Store at 4°C.
Form Solid
Formulation 100% NF-κB Activation Inhibitor VI
Quantity 25 mg
For Use With (Application) NF-κB pathway inhibition
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