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NF-YC Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501561787
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50-156-1787 10 μL
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Catalog No. 50-156-1787 Supplier Bethyl Laboratories, Inc Supplier No. A302107AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold ""handshake"" motif in a manner analogous to the histone proteins, H2B and H2A, respectively.

Specifications

Antigen NF-YC
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene NFYC
Gene Accession No. Q13952
Gene Alias Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC
Gene Symbols NFYC
Host Species Rabbit
Immunogen Between 408 and 458
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4802
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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