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Invitrogen™ NFATC3 Polyclonal Antibody
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Catalog No. PIPA578403
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100 μL
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PIPA578403 100 μL
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Catalog No. PIPA578403 Supplier Invitrogen™ Supplier No. PA578403
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Description

Rabbit Polyclonal Antibody

Positive Control: Jurkat, Raji, NCI-H929, mouse thymus Predicted Reactivity: Human (90%), Rat (96%), Bovine (92%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFATC3
Applications Western Blot
Classification Polyclonal
Concentration 1.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene NFATC3
Gene Accession No. P97305, Q12968
Gene Alias C80703; D8Ertd281e; NFAC3; NFAT4; NF-AT4; NFATC3; NF-ATc3; NFATx; NFC3; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3; nuclear factor of activated T-cells 3; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
Gene Symbols NFATC3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of mouse NFAT4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18021, 4775
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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