NFATC3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-2056	Proteintech Group Inc 182221AP150UL	150 μL

Description

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.

Specifications

• Antigen: NFATC3
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P97305, Q12968
• Gene ID (Entrez): 18021, 4775
• Immunogen: NFATC3 Fusion Protein Ag12985
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NFATC3

• Concentration: 0.34 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: NF AT4, NF ATc3, NFAT4, NFATC3, NFATX
• Gene Symbols: Nfatc3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody