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NFE2 Mouse anti-Human, Clone: 1D7C8, Proteintech
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Catalog No. p-7213230 Shop All Proteintech Group Inc Products
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50-173-6862 150 μL
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Catalog No. 50-173-6862 Supplier Proteintech Group Inc Supplier No. 664361IG150UL
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Description

Mouse Monoclonal Antibody

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Specifications

Antigen NFE2
Applications Western Blot
Classification Monoclonal
Clone 1D7C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NFE2
Gene Accession No. Q16621
Gene Alias Leucine zipper protein NF E2, NF E2, NFE2, p45, p45 NF E2
Gene Symbols NFE2
Host Species Mouse
Immunogen NFE2 Fusion Protein Ag1570
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4778
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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