Invitrogen™ NFE4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549450

Catalog No. PA549450

Description

NFE4 Polyclonal Antibody for Western Blot

Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.

Specifications

• Antigen: NFE4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFE4
• Gene Alias: fetal globin activator NF-E4; gamma-globin gene activator; NFE4; NF-E4; nuclear factor, erythroid 4; transcription factor NF-E4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 58160
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.45 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q86UQ8
• Gene Symbols: NFE4
• Immunogen: KLH conjugated synthetic peptide between 135-169 amino acids from the C-terminal region of human NFE4.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG