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Invitrogen™ NFIB Monoclonal Antibody (1H4)
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Catalog No. PIMA542392
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100 μL
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PIMA542392 100 μL
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Catalog No. PIMA542392 Supplier Invitrogen™ Supplier No. MA542392
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Description

Mouse Monoclonal Antibody

Positive Control: SH-SY-5Y, rat heart tissue, human prostate tissue, human pancreas tissue, mouse liver tissue lysate. Subcellular Location: Nucleus.

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFIB
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1H4
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene NFIB
Gene Accession No. O00712, P97863
Gene Alias 6720429L07Rik; CCAAT-box-binding transcription factor; CTF; E030026I10Rik; HMGIC/NFIB; NF1-B; NF-I/B; Nfib; NFI-B; NFIB2; NFIB3; NFI-RED; nuclear factor 1 B-type; nuclear factor 1/B; nuclear factor I B; nuclear factor I/B; olfactory epithelium nuclear factor I-B; TGGCA-binding protein
Gene Symbols NFIB
Host Species Mouse
Immunogen Recombinant full length protein corresponding to human NFIB/NF1B2.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18028, 29227, 4781
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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