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NFIB/NF1B2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981766
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50-198-1766 100 μL
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Catalog No. 50-198-1766 Supplier Bioss Supplier No. BS11899R
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Description

Rabbit Polyclonal Antibody

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Specifications

Antigen NFIB/NF1B2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NFIB
Gene Accession No. O00712
Gene Alias 6720429L07Rik; CCAAT-box-binding transcription factor; CTF; E030026I10Rik; HMGIC/NFIB; NF1-B; NF-I/B; NFIB; NFI-B; NFIB2; NFIB3; NFI-RED; Nuclear factor 1 B-type; nuclear factor 1/B; nuclear factor I B; Nuclear factor I/B; olfactory epithelium nuclear factor I-B; TGGCA-binding protein
Gene Symbols NFIB
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NFIB/NF1B2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4781
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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