Invitrogen™ NFkB p52/p100 Polyclonal Antibody

Catalog No.	Quantity
PIPA130410	1 mL

Catalog No. PIPA130410

Supplier: Invitrogen™ PA130410

Description

Rabbit Polyclonal Antibody

PA1-30410 detects NFkB p52 from rat, human, mouse samples.

The NFkB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A cDNA has been isolated that encodes an alternative DNA binding subunit of NFkB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.

Specifications

• Antigen: NFkB p52/p100
• Applications: Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.2% gelatin and 0.1% sodium azide
• Gene: Nfkb2
• Gene Accession No.: Q00653, Q9WTK5
• Gene Alias: CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; LYT10; LYT-10; NF kappaB2; NF KB; NF-kappaB2; nfkb p100; NF-kB p52/p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2
• Gene Symbols: Nfkb2
• Host Species: Rabbit
• Immunogen: Synthetic peptide (Mouse) (C terminal).
• Purification Method: Affinity chromatography
• Quantity: 1 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18034, 309452, 4791
• Target Species: Human, Mouse, Rat
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov