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Invitrogen™ NFRKB Polyclonal Antibody
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Catalog No. PIPA552384
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100 μL
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PIPA552384 100 μL
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Catalog No. PIPA552384 Supplier Invitrogen™ Supplier No. PA552384
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SLPMLEERVL DWQSSPASSL NSWFSAAPNW AELVLPALQY LAGESRAVPS SFSPFVEFKE KTQQWKLLGQ SQDNEKELAA LFQLWLETKD QAFCKQENED SSDATTPVPR VRTDYVVRPS Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFRKB
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NFRKB
Gene Accession No. Q6P4R8
Gene Alias A530090G11Rik; DNA-binding protein R kappa B; DNA-binding protein R kappa-B; INO80 complex subunit G; INO80G; NFRKB; nuclear factor related to kappa B binding protein; nuclear factor related to kappaB binding protein; nuclear factor related to kappa-B-binding protein
Gene Symbols NFRKB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NFRKB. Recombinant protein control fragment (Product #RP-89399).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4798
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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