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Invitrogen™ NFX1 Polyclonal Antibody
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Catalog No. PIPA546843
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PIPA546843 100 μL
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Catalog No. PIPA546843 Supplier Invitrogen™ Supplier No. PA546843
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Description

Rabbit Polyclonal Antibody

Peptide sequence: TLTGVLEREM QARPPPPIPH HRHQSDKNPG SSNLQKITKE PIIDYFDVQD Sequence homology: Cow: 85%; Dog: 85%; Human: 100%; Mouse: 76%; Rabbit: 85%; Rat: 85%.

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFX1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene NFX1
Gene Accession No. Q12986
Gene Alias 1300017N15Rik; 3000003M19Rik; DKFZp779G2416; MGC20369; m-Nfx.1; NFX.1; Nfx1; NFX2; nuclear transcription factor, X box-binding protein 1; nuclear transcription factor, X-box binding 1; TEG-42; testis expressed gene 42; Tex42; transcriptional repressor NF-X1; X-box binding 1
Gene Symbols NFX1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human NFX1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4799
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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