β-Nicotinamide Adenine Dinucleotide, MP Biomedicals™

Description

Serves as a coenzyme of the dehydrogenases. β-Nicotinamide Adenine Dinucleotide, MP Biomedicals is one of the biologically active forms of nicotinic acid that occurs in living cells primarily in the oxidized state. It is a major electron acceptor mol

• Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols
• Usually acts as a hydrogen acceptor, forming NADH, which then serves as a hydrogen donor in the respiratory chain
• Acts as a coenzyme for hydride-transfer enzymes
• Used as a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins
• Recently reported to be a P2Y11 agonist

Specifications

Chemical Identifiers

• CAS: 53-84-9
• Molecular Formula: C21H27N7O14P2
• Molecular Weight (g/mol): 663.43
• MDL Number: MFCD00150377
• InChI Key: BAWFJGJZGIEFAR-WIWLTUSXNA-N
• Synonym: nicotinamide adenine dinucleotide, nad+, diphosphopyridine nucleotide, nad-oxidized, nicotinamide-adenine dinucleotide, dpn-ox, beta-nicotinamide adenine dinucleotide, dpn+, nad, nad +
• PubChem CID: 15938971
• ChEBI: CHEBI:57540
• IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• SMILES: NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O

• pH: 2 to 4 (1% aq. soln.)
• Quantity: 25 g
• Solubility Information: Soluble in water (200mg/mL)
• Formula Weight: 663.40 (anhydrous)
• Percent Purity: ≥93%
• Physical Form: Powder

Safety and Handling

Recommended Storage

−20°C, desiccate