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Invitrogen™ NIFK Monoclonal Antibody (18E148)
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Catalog No. 01676476
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100 μg
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Catalog No. Quantity
01-676-476 100 μg
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Catalog No. 01-676-476 Supplier Invitrogen™ Supplier No. MA141143
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Description

Mouse Monoclonal Antibody

Suggested positive control: antigen standard for MKI67IP (transient overexpression lysate), HeLa or Ramos.

NIFK, also known as nucleolar protein interacting with the forkhead homolog protein, is a gene associated with several cancer types and is considered a potential prognostic biomarker. This gene functions within the nucleolus and plays a critical role in cellular proliferation, metastasis, and invasiveness, particularly noted in hepatocellular carcinoma (HCC) and colorectal cancer. NIFK expression is regulated via several pathways, including the MYC proto-oncogene pathway, and its silencing can lead to decreased fatty acid synthesis in colorectal cancer cells. Furthermore, it's involved in the regulation of innate immunity through pathways such as NF-kB in specific cancer cells. Due to its involvement in cancer progression, NIFK is being explored as a therapeutic target and holds promise for advancing precision medicine strategies across various cancer treatments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NIFK
Applications Western Blot
Classification Monoclonal
Clone '18E148
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene Nifk
Gene Accession No. Q9BYG3
Gene Alias AI852665; C130020J04Rik; hNIFK; Ki67ip; MKI67 (FHA domain) interacting nucleolar phosphoprotein; MKI67 FHA domain-interacting nucleolar phosphoprotein; MKI67IP; mNIFK; NIFK; NOPP34; nucleolar phosphoprotein Nopp34; nucleolar protein interacting with the FHA domain of MKI67; nucleolar protein interacting with the FHA domain of pKI-67; spermatogenesis-related protein (Srp)
Gene Symbols Nifk
Host Species Mouse
Immunogen Synthetic peptide corresponding to a portion of human NIFK between amino acids 100-200.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84365
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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