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Invitrogen™ NIFK Polyclonal Antibody
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Catalog No. PIPA583283
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PIPA583283 100 μL
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Catalog No. PIPA583283 Supplier Invitrogen™ Supplier No. PA583283
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IDYDFPSLIL QKTESISKTN RQTSTKGQVL RKKKKKVSGT LDTPEKTVDS QGPTPVCTPT FLERRKSQVA ELNDDDKDDE I Highest antigen sequence indentity to the following orthologs: Mouse - 48%, Rat - 43%.

NIFK, also known as nucleolar protein interacting with the forkhead homolog protein, is a gene associated with several cancer types and is considered a potential prognostic biomarker. This gene functions within the nucleolus and plays a critical role in cellular proliferation, metastasis, and invasiveness, particularly noted in hepatocellular carcinoma (HCC) and colorectal cancer. NIFK expression is regulated via several pathways, including the MYC proto-oncogene pathway, and its silencing can lead to decreased fatty acid synthesis in colorectal cancer cells. Furthermore, it's involved in the regulation of innate immunity through pathways such as NF-kB in specific cancer cells. Due to its involvement in cancer progression, NIFK is being explored as a therapeutic target and holds promise for advancing precision medicine strategies across various cancer treatments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NIFK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Nifk
Gene Accession No. Q9BYG3
Gene Alias AI852665; C130020J04Rik; hNIFK; Ki67ip; MKI67 (FHA domain) interacting nucleolar phosphoprotein; MKI67 FHA domain-interacting nucleolar phosphoprotein; MKI67IP; mNIFK; NIFK; NOPP34; nucleolar phosphoprotein Nopp34; nucleolar protein interacting with the FHA domain of MKI67; nucleolar protein interacting with the FHA domain of pKI-67; spermatogenesis-related protein (Srp)
Gene Symbols Nifk
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NIFK. Recombinant protein control fragment (Product #RP-104083).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84365
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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