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NIPA Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563865
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50-156-3865 20 μL
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Catalog No. 50-156-3865 Supplier Bethyl Laboratories, Inc Supplier No. A302942AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Specifications

Antigen NIPA
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ZC3HC1
Gene Accession No. Q86WB0
Gene Alias OTTHUMP00000212330; hNIPA; hematopoietic stem/progenitor cell protein 216; nuclear interacting partner of anaplastic lymphoma kinase (ALK); nuclear interaction partner of ALK; nuclear-interacting partner of ALK; nuclear-interacting partner of anaplastic lymphoma kinase; zinc finger C3HC-type protein 1; zinc finger, C3HC type 1
Gene Symbols ZC3HC1
Host Species Rabbit
Immunogen Between 300 and 350
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51530
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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