Thermo Scientific Chemicals Nitro Blue Tetrazolium chloride, tech. 90%

Description

CAS: 298-83-9 | C40H30Cl2N10O6 | 817.644 g/mol

Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that

Specifications

Chemical Identifiers

• CAS: 298-83-9
• Molecular Formula: C40H30Cl2N10O6
• Molecular Weight (g/mol): 817.644
• MDL Number: MFCD00150013
• InChI Key: FSVCQIDHPKZJSO-UHFFFAOYSA-L
• Synonym: nitrotetrazolium blue chloride, nitro bt, nitro blue tetrazolium, nbt, nitro blue tetrazolium chloride, p-nitrotetrazolium blue, nitrotetrazolium blue, nitroblue tetrazolium chloride, p-nitro blue tetrazolium chloride, nitro tetrazolium bt
• PubChem CID: 9281
• ChEBI: CHEBI:9505
• IUPAC Name: 2-[2-methoxy-4-[3-methoxy-4-[3-(4-nitrophenyl)-5-phenyltetrazol-2-ium-2-yl]phenyl]phenyl]-3-(4-nitrophenyl)-5-phenyltetrazol-2-ium;dichloride
• SMILES: COC1=C(C=CC(=C1)C2=CC(=C(C=C2)[N+]3=NC(=NN3C4=CC=C(C=C4)[N+](=O)[O-])C5=CC=CC=C5)OC)[N+]6=NC(=NN6C7=CC=C(C=C7)[N+](=O)[O-])C8=CC=CC=C8.[Cl-].[Cl-]

• Melting Point: ∼190°C (decomposition)
• Quantity: 0.5 g
• Beilstein: 4115923
• Solubility Information: Soluble in water,ethanol and methanol.
• Formula Weight: 817.65
• Percent Purity: 90%
• Grade: Technical
• Chemical Name or Material: Nitro Blue Tetrazolium chloride

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	206-067-4
RTECSNumber	XF8045000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only