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Invitrogen™ NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), PE

Rat Monoclonal Antibody

Supplier:  Invitrogen™ A15417

Encompass_Preferred

Catalog No. 50-113-7707


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Description

Description

NKG2A/NKG2C/NKG2E Monoclonal Antibody for Flow

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NKG2A/NKG2C/NKG2E
Monoclonal
0.1 mg/mL
PBS with <0.1% sodium azide; pH 7.5
0
Klrc1, Klrc2, Klrc3
epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer.
100 μg
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry
20d5
PE
Klrc1
CD159a; cd159c; cd159e; Cluster of Differentiation 159a; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; Klrc1; Klrc2; Klrc3; natural killer cell group 2E cell receptor; NKG2; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; NKG2C; Nkg2e
Rat
purified
RUO
16641, 16642, 58179
4°C, store in dark, DO NOT FREEZE!
Liquid
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