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Invitrogen™ NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), PE
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Catalog No. 501137707
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100 μg
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Catalog No. Quantity
50-113-7707 100 μg
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Catalog No. 50-113-7707 Supplier Invitrogen™ Supplier No. A15417
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Description

Rat Monoclonal Antibody

NKG2A/NKG2C/NKG2E Monoclonal Antibody for Flow

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NKG2A/NKG2C/NKG2E
Applications Flow Cytometry
Classification Monoclonal
Clone 20d5
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with <0.1% sodium azide; pH 7.5
Gene Klrc1
Gene Accession No. 0
Gene Alias CD159a; cd159c; cd159e; Cluster of Differentiation 159a; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; Klrc1; Klrc2; Klrc3; natural killer cell group 2E cell receptor; NKG2; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; NKG2C; Nkg2e
Gene Symbols Klrc1, Klrc2, Klrc3
Host Species Rat
Immunogen epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer.
Purification Method purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16641, 16642, 58179
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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