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Invitrogen™ NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), PE
Rat Monoclonal Antibody
Supplier: Invitrogen™ A15417

Description
NKG2A/NKG2C/NKG2E Monoclonal Antibody for Flow
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Specifications
NKG2A/NKG2C/NKG2E | |
Monoclonal | |
0.1 mg/mL | |
PBS with <0.1% sodium azide; pH 7.5 | |
0 | |
Klrc1, Klrc2, Klrc3 | |
epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer. | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG2a κ |
Flow Cytometry | |
20d5 | |
PE | |
Klrc1 | |
CD159a; cd159c; cd159e; Cluster of Differentiation 159a; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; Klrc1; Klrc2; Klrc3; natural killer cell group 2E cell receptor; NKG2; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; NKG2C; Nkg2e | |
Rat | |
purified | |
RUO | |
16641, 16642, 58179 | |
4°C, store in dark, DO NOT FREEZE! | |
Liquid |
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