Invitrogen™ NKG2A/NKG2C/NKG2E Monoclonal Antibody (20d5), PE

Rat Monoclonal Antibody

Supplier:  Invitrogen™ A15417

Catalog No. 50-113-7707

Description

NKG2A/NKG2C/NKG2E Monoclonal Antibody for Flow

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Specifications

• Antigen: NKG2A/NKG2C/NKG2E
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with <0.1% sodium azide; pH 7.5
• Gene Accession No.: 0
• Gene Symbols: Klrc1, Klrc2, Klrc3
• Immunogen: epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: 20d5
• Conjugate: PE
• Gene: Klrc1
• Gene Alias: CD159a; cd159c; cd159e; Cluster of Differentiation 159a; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; Klrc1; Klrc2; Klrc3; natural killer cell group 2E cell receptor; NKG2; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; NKG2C; Nkg2e
• Host Species: Rat
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 16641, 16642, 58179
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid