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Invitrogen™ NMDAR2A Monoclonal Antibody (N327A/38), APC
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Catalog No. PIMA545611
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Quantity:
100 μg
Catalog No. Quantity
PIMA545611 100 μg
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Catalog No. PIMA545611

Supplier: Invitrogen™ MA545611

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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45611 was sufficient for detection of GluN2A/NR2A in 20 μg of COS cells transiently transfected with GFP-tagged NR2A lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 170kDa. Does not react with NR2B. This antibody was formerly sold as clone S327A-38.

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NMDAR2A
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N327A/38
Concentration 1 mg/mL
Conjugate APC
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
Gene Grin2a
Gene Accession No. P35436, Q00959, Q12879
Gene Alias EPND; FESD; GluN2A; GluRepsilon1; glutamate [NMDA] receptor subunit epsilon-1; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor; glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Grin2a; hNR2A; LKS; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531
Gene Symbols Grin2a
Host Species Mouse
Immunogen Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14811, 24409, 2903
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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