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Invitrogen™ NMDAR2A Polyclonal Antibody
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Catalog No. A6473
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A6473 10 μg
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Catalog No. A6473 Supplier Invitrogen™ Supplier No. A6473
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Description

Rabbit Polyclonal Antibody

This antibody recognizes the 180 kDa 2A subunit from rat, mouse and human, and does not cross-react with the 2B or 2C subunits. Storage and reconstitution: when stored at -20°C or below, the lyophilized antibody should retain full activity for over one year. Reconstitute using 50 μL PBS, pH 7.4, to yield a 0.2 mg/mL solution. If storing at 0-4°C, add sodium azide to a final concentration of 2mM. For longer storage, divide the solution into aliquots and freeze at -20°C, avoiding freeze/thaw cycles.

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NMDAR2A
Applications ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Grin2a
Gene Accession No. P35436, Q00959, Q12879
Gene Alias EPND; FESD; GluN2A; GluRepsilon1; glutamate [NMDA] receptor subunit epsilon-1; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor; glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Grin2a; hNR2A; LKS; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531
Gene Symbols Grin2a
Host Species Rabbit
Immunogen Fusion protein containing amino acid residues 1253-1391 of the C-terminal region of rat brain subunit 2A.
Purification Method IgG fraction
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14811, 24409, 2903
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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