Invitrogen™ NOD4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521017

Catalog No. PIPA521017

Description

A suggested positive control is EL4 cell lysate. PA5-21017 can be used with blocking peptide PEP-1131.

NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-kappa-B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Specifications

• Antigen: NOD4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NLRC5
• Gene Alias: AI451557; AK220210; Caterpiller protein 16.1; CLR16.1; copine II; Cpne2; NLR family CARD domain containing 5; NLR family, CARD domain containing 5; Nlrc5; NOD27; NOD4; NOD-like receptor C5; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5; nucleotide-binding oligomerization domains 27; protein NLRC5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 434341, 84166
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: C3VPR6, Q86WI3
• Gene Symbols: NLRC5
• Immunogen: An 18 amino acid peptide near the amino terminus of human NOD4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG