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Apexbio Technology LLC ML-354 89159-60-4 25mg
SDP

Supplier:  Apexbio Technology LLC C305825

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ML-354 (CAS 89159-60-4) is an indole-derived antagonist of protease-activated receptor 4 (PAR4) exhibiting an IC50 of 140 nM PAR4 is a G-protein-coupled receptor activated via proteolytic cleavage by serine proteases and serves as a thrombin receptor on human platelets By inhibiting PAR4 ML-354 provides a tool to investigate PAR4-mediated platelet activation pathways Its selectivity over PAR1 supports its use in the study of thrombotic mechanisms and the evaluation of PAR4 as a therapeutic target in platelet-related disorders Current research is focused on the compound s in vitro and in vivo pharmacological characterization

Catalog No. 50-000-87829


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