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Invitrogen™ NOTCH2NL Polyclonal Antibody
Rabbit Polyclonal Antibody
$237.00 - $539.50
Specifications
| Antigen | NOTCH2NL |
|---|---|
| Concentration | 1 mg/mL |
| Content And Storage | -20°C |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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PIPA5119312
|
Invitrogen™
PA5119312 |
200 μL |
Each for $539.50
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PIPA5121738
|
Invitrogen™
PA5121738 |
20 μL |
Each for $237.00
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Description
NOTCH2NL Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway (PubMed:29856954, PubMed:29856955, PubMed:29561261). Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production (PubMed:29856954). Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect (PubMed:29856954). Enhances Notch signaling pathway in a non-cell-autonomous manner via direct interaction with NOTCH2 (PubMed:29856954). Also promotes Notch signaling pathway in a cell-autonomous manner through inhibition of cis DLL1-NOTCH2 interactions, which promotes neuronal differentiation. [UniProt].Specifications
| NOTCH2NL | |
| -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| NOTCH2NL | |
| N2N; notch 2 N-terminal like; Notch homolog 2 N-terminal like protein; notch homolog 2 N-terminal-like protein; Notch homolog 2 N-terminal-like protein A; Notch homolog 2 N-terminal-like protein C; NOTCH2NL; NOTCH2NLA; NOTCH2NLC | |
| NOTCH2NL | |
| Primary | |
| Antigen affinity chromatography |
| 1 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.05% ProClin 300 | |
| Q7Z3S9 | |
| 388677 | |
| Recombinant protein Notch2 N-Terminal Like Protein. | |
| Antibody |
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