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Novus Biologicals™ Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand
SDP

Catalog No. NBP226231 Shop All R&D Systems Products
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0.5 mg
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NBP226231 0.5 mg
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Catalog No. NBP226231 Supplier Novus Biologicals™ Supplier No. NBP226231

Description

Applications: Functional

Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 ligand is a low molecular weight synthetic molecule of the Imidazoquinoline family. It has potent immunostimulatory activity. It stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 up-regulation.

  • Species: Human
  • Stimulation of TLR8 has been achieved with 0.5-5μg/mL

Recommended Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specifications

Buffer DMSO
Content And Storage Store at -20°C.
For Use With (Application) Identity determined by MS, 1H-NMR and 13C-NMR. This product is useful for activation of mouse TLR7 and human TLR7 and TLR8. Stimulation of TLR8 has been achieved with 0.5-5 ug/mL. Use in functional assays reported in scientific literature (PMID 26134251).
Product Type Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand
Purity >98%, by HPLC.
Quantity 0.5 mg
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