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Invitrogen™ NOX3 Polyclonal Antibody
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Catalog No. PIPA599669
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100 μL
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PIPA599669 100 μL
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Catalog No. PIPA599669 Supplier Invitrogen™ Supplier No. PA599669
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Nox3.

The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide. NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith. It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOX3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NOX3
Gene Accession No. Q9HBY0
Gene Alias GP91-3; gp91phox homolog 3; head-tilt; het; Mitogenic oxidase 2; MOX2; MOX-2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NAPDH oxidase 3; nmf250; Nox3; NOX-3
Gene Symbols NOX3
Host Species Rabbit
Immunogen A synthesized peptide derived from human NOX3(Accession Q9HBY0), corresponding to amino acid residues Y127-G177.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50508
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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