NPR2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-5992	Proteintech Group Inc 551131AP150UL	150 μL

Description

The antibody is specific to NPR2.

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Specifications

• Antigen: NPR2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P20594, Q6VVW5
• Gene ID (Entrez): 230103, 4882
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NPR2

• Concentration: 0.38 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AMDM, ANP B, ANPR B, ANPRB, GC B, Guanylate cyclase B, GUC2B, GUCY2B, Natriuretic Peptide Receptor B, NPR2, NPRB
• Gene Symbols: NPR2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody