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Invitrogen™ NPTX2 Polyclonal Antibody
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Catalog No. p-7184302
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100 μL
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PIPA5111299 100 μL
PIPA5111466 100 μL
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Catalog No. PIPA5111299 Supplier Invitrogen™ Supplier No. PA5111299
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ELERQLLRKV AELEDEKSLL HNETSAHRQK TESTLNALLQ RVTELERGNS AFKSPDAFKV SLPLRTNYLY GKIKKTLP Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 100%.

Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson's disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPTX2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NPTX2
Gene Accession No. P47972
Gene Alias apexin; Narp; neuro activity regulated petaxin; neuronal activity-regulated pentaxin; neuronal activity-regulated pentraxin; neuronal pentraxin 2; neuronal pentraxin II; Neuronal pentraxin-2; NP2; NP-II; Nptx2
Gene Symbols NPTX2
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human NPTX2. Recombinant protein control fragment (Product #RP-103055).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4885
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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