Invitrogen™ NPY Monoclonal Antibody (8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ ABS0280802

Catalog No. 01-670-111

Description

ABS 028-08-02 detects Neuropeptide Y in human and rat samples. ABS 028-08-02 has been successfully used in ELISA and immunohistochemistry (paraffin) procedures. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

Specifications

• Antigen: NPY
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P01303, P07808, P57774
• Gene Symbols: NPY
• Immunogen: Synthetic peptide made to human/rat NPY.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
• Clone: 8
• Conjugate: Unconjugated
• Gene: NPY
• Gene Alias: 0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100912228, 109648, 24604, 4852
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

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