NPY Monoclonal Antibody (OTI8F8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808282

Catalog No. 50-168-2029

Description

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase , regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

Specifications

• Antigen: NPY
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P01303
• Gene Symbols: NPY
• Immunogen: Full length human recombit protein of human NPY produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI8F8
• Conjugate: Unconjugated
• Gene: NPY
• Gene Alias: PYY4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4852
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid