Invitrogen™ NPY Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA124891

Catalog No. PIPA124891

Description

Recommended positive controls: rat brain. PA1-24891 is expected to cross react with chicken (99% conserved) due to sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

Specifications

• Antigen: NPY
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPY
• Gene Alias: 0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02
• Host Species: Rabbit
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Sheep, Pig
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Frozen)
• Concentration: Conc. Not Determined
• Formulation: whole serum with 15mM sodium azide
• Gene Accession No.: P01303, P01304, P07808, P14765, P57774
• Gene Symbols: NPY
• Immunogen: Synthetic Neuropeptide Y, conjugated to KLH, corresponding to the porcine protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 100912228, 109648, 24604, 397304, 443508, 4852
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov