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NR1H3 Mouse anti-Human, Rat, Clone: 4A4F7, Proteintech
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Catalog No. 501736259 Shop All Proteintech Group Inc Products
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Catalog No. Quantity
50-173-6259 150 μL
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Catalog No. 50-173-6259 Supplier Proteintech Group Inc Supplier No. 601341IG150UL
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Description

Mouse Monoclonal Antibody

The liver X receptors, LXRA and LXRB (NR1H2), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

Specifications

Antigen NR1H3
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 4A4F7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NR1H3
Gene Accession No. Q13133, Q62685
Gene Alias Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1
Gene Symbols Nr1h3
Host Species Mouse
Immunogen NR1H3 Fusion Protein Ag6184
Purification Method Caprylic Acid Precipitation
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10062, 58852
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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