Invitrogen™ NR5A1 Monoclonal Antibody (N1665)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 434200

Catalog No. 43-420-0

Description

This antibody specifically recognizes human SF-1 and cross reacts with mouse and rat SF-1.

Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 has been shown to be essential for fetal development of the hypothalamus, pituitary gland, gonads, and the adrenal gland. SF-1 has been shown to promote transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family. SF-1 contains two activation function domains, designated AF1 and AF2, common to many nuclear steroid receptors which have been shown to be necessary for interaction with other nuclear receptors as well as coactivators and corepressors including steroid receptor coactivator-1 (SRC-1), glucocorticoid receptor interacting protein 1 (GRIP1), cAMP response element binding protein (CREB) binding protein (CBP) and silencing mediator of retinoid acid and thyroid hormone receptor (SMRT).

Specifications

• Antigen: NR5A1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: physiological saline with 0.1% sodium azide
• Gene Accession No.: P33242, P50569, Q13285
• Gene Symbols: Nr5a1
• Immunogen: BALB/c mouse immunized with E.coli-expressed recombinant human SF-1 (218-461aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: N1665
• Conjugate: Unconjugated
• Gene: Nr5a1
• Gene Alias: Ad4BP; Ad4BP/SF-1; adrenal 4 binding protein; Adrenal 4 binding protein (AD4BP); adrenal 4-binding protein; ELP; ELP-3; Embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; FTZ1; FTZF1; Ftz-F1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; Fushi tarazu factor homolog 1 (FTZ1); hSF-1; Nr5a1; nuclear receptor AdBP4; nuclear receptor subfamily 5 group A member 1; Nuclear receptor subfamily 5 group A member 1 (NR5A1); nuclear receptor subfamily 5, group A, member 1; POF7; SF1; SF-1; SPGF8; SRXY3; Steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; Steroidogenic factor 1; Steroidogenic factor 1 (SF1); steroidogenic factor 1 nuclear receptor; steroidogenic factor-1; STF1; STF-1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2516, 26423, 83826
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 1 month. For long term storage store at -20°C
• Form: Liquid