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Invitrogen™ NRF1 Recombinant Rabbit Monoclonal Antibody (JM89-63)
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Catalog No. PIMA532782 Shop All Thermo Scientific Products
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PIMA532782 100 μL
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Catalog No. PIMA532782 Supplier Invitrogen™ Supplier No. MA532782
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NRF1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone JM89-63
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene NRF1
Gene Accession No. Q16656, Q62792, Q9WU00
Gene Alias Alpha palindromic-binding protein; alpha-pal; C87038; D6Ertd415e; EWG; LOW QUALITY PROTEIN: nuclear respiratory factor 1; Nfe2l1_retired; Not really finished protein; nrf; Nrf1; NRF-1; nrf1 protein; nrl; nuclear respiratory factor 1; nuclear respiratory factor-1; SC:BZ3C13.1; SC:bZ3C13.2; transcription factor; ube2h
Gene Symbols NRF1
Host Species Rabbit
Immunogen Synthetic peptide within Human NRF1 aa 333-382.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18181, 312195, 4899
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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