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NRF2/NFE2L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 163961AP150UL

Encompass_Preferred

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Catalog No. 50-553-534


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Description

Description

Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription activator which plays a key role in protecting the cell from oxidative stress and inflammation. It is primarily localized in the cytoplasm under normal conditions, but under conditions of oxidative stress, Nrf2 migrates to the nucleus to upregulate expression of genes with ARE (antioxidant response elements) in the promoter region. The upregulated genes include those involved in cellular protection, drug transport, detoxification, and anti-oxidant defense. The protein is ubiquitously expressed in various tissues, with the highest levels found in kidney, muscle, lung, heart, liver, and brain.
Specifications

Specifications

NRF2/NFE2L2
Polyclonal
Unconjugated
NFE2L2
HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, NRF2
Rabbit
Antigen Affinity Chromatography
RUO
18024, 4780, 83619
-20°C
Liquid
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O54968, Q16236, Q60795
Nfe2l2
NRF2, NFE2L2 Fusion Protein Ag9489
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
SDS
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