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  6. NRF2/NFE2L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

NRF2/NFE2L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. p-7208041 Shop All Proteintech Group Inc Products
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50-553-534 150 μL
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Catalog No. 50-553-534 Supplier Proteintech Group Inc Supplier No. 163961AP150UL
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Description

Rabbit Polyclonal Antibody

Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription activator which plays a key role in protecting the cell from oxidative stress and inflammation. It is primarily localized in the cytoplasm under normal conditions, but under conditions of oxidative stress, Nrf2 migrates to the nucleus to upregulate expression of genes with ARE (antioxidant response elements) in the promoter region. The upregulated genes include those involved in cellular protection, drug transport, detoxification, and anti-oxidant defense. The protein is ubiquitously expressed in various tissues, with the highest levels found in kidney, muscle, lung, heart, liver, and brain.

Specifications

Antigen NRF2/NFE2L2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NFE2L2
Gene Accession No. O54968, Q16236, Q60795
Gene Alias HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, NRF2
Gene Symbols Nfe2l2
Host Species Rabbit
Immunogen NRF2, NFE2L2 Fusion Protein Ag9489
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18024, 4780, 83619
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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