NRF2/NFE2L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-553-534	Proteintech Group Inc 163961AP150UL	150 μL

Description

Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription activator which plays a key role in protecting the cell from oxidative stress and inflammation. It is primarily localized in the cytoplasm under normal conditions, but under conditions of oxidative stress, Nrf2 migrates to the nucleus to upregulate expression of genes with ARE (antioxidant response elements) in the promoter region. The upregulated genes include those involved in cellular protection, drug transport, detoxification, and anti-oxidant defense. The protein is ubiquitously expressed in various tissues, with the highest levels found in kidney, muscle, lung, heart, liver, and brain.

Specifications

• Antigen: NRF2/NFE2L2
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O54968, Q16236, Q60795
• Gene ID (Entrez): 18024, 4780, 83619
• Immunogen: NRF2, NFE2L2 Fusion Protein Ag9489
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: NFE2L2

• Concentration: 0.47 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, NRF2
• Gene Symbols: Nfe2l2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody