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NSC 109555 ditosylate, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
66748-43-4
C33H40N10O7S2
752.866
DIQGNVANOSOABS-UHFFFAOYSA-N
2,2'-carbonylbis azanediyl bis 4,1-phenylene bis ethan-1-yl-1-ylidene bis hydrazinecarboximidamide 4-methylbenzenesulfonate
118797492
1,3-bis[4-[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]urea;4-methylbenzenesulfonic acid
CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CC(=NN=C(N)N)C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)C(=NN=C(N)N)C
This item is not returnable. View return policy
66748-43-4
C33H40N10O7S2
752.866
DIQGNVANOSOABS-UHFFFAOYSA-N
2,2'-carbonylbis azanediyl bis 4,1-phenylene bis ethan-1-yl-1-ylidene bis hydrazinecarboximidamide 4-methylbenzenesulfonate
118797492
1,3-bis[4-[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]urea;4-methylbenzenesulfonic acid
CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CC(=NN=C(N)N)C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)C(=NN=C(N)N)C

Selective Chk2 inhibitor

Selective, reversible, ATP-competitive Chk2 inhibitor (IC 50 = 0.2 μM) that displays no effect on a range of other kinases including Chk1 (IC 50 > 10 μM). Inhibits histone H1 phosphorylation (IC 50 = 0.24 μM) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias in vivo.
Quantity 50mg
Formula Weight 752.86
Percent Purity >98%
Chemical Name or Material NSC 109555 ditosylate

Recommended Storage : Store at -20°C