Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. NSC 109555 ditosylate, Tocris Bioscience™

NSC 109555 ditosylate, Tocris Bioscience™

Catalog No. 303450
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
30-345-0 50 mg
30-341-0 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 30-345-0 Supplier R&D Systems Supplier No. 3034/50
This item is not returnable. View return policy

Description

Selective Chk2 inhibitor

Selective, reversible, ATP-competitive Chk2 inhibitor (IC50 = 0.2 μM) that displays no effect on a range of other kinases including Chk1 (IC50 > 10 μM). Inhibits histone H1 phosphorylation (IC50 = 0.24 μM) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias in vivo.

Chemical Identifiers

CAS 66748-43-4
Molecular Formula C33H40N10O7S2
Molecular Weight (g/mol) 752.866
InChI Key DIQGNVANOSOABS-UHFFFAOYSA-N
Synonym 2,2'-carbonylbis azanediyl bis 4,1-phenylene bis ethan-1-yl-1-ylidene bis hydrazinecarboximidamide 4-methylbenzenesulfonate
PubChem CID 118797492
IUPAC Name 1,3-bis[4-[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]urea;4-methylbenzenesulfonic acid
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CC(=NN=C(N)N)C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)C(=NN=C(N)N)C

Specifications

Quantity 50 mg
Formula Weight 752.86
Percent Purity >98%
Chemical Name or Material NSC 109555 ditosylate

Safety and Handling

Recommended Storage Store at -20°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.