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NSC 697923, Tocris Bioscience™

Catalog No. 485810
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective UBE2N inhibitor

Selective inhibitor of the E2 ubiquitin (Ub) conjugating enzyme UBE2N (Ubc13). Inhibits UBE2N-Ub conjugation and activity of the UBE2N-Ueva1A complex. Has no effect on UbcH5c activity. Inhibits NF-κB activation in diffuse large B-cell lymphoma (DLBCL) cells. Inhibits cell growth and induces apoptosis in DLBCL and neuroblastoma (NB) cell lines. Supresses NB cell xenograft tumor growth in vivo.

Chemical Identifiers

CAS 343351-67-7
Molecular Formula C11H9NO5S
Molecular Weight (g/mol) 267.255
InChI Key GAUHIPWCDXOLCZ-UHFFFAOYSA-N
Synonym 2-4-methylphenyl sulfonyl-5-nitrofuran, 2-nitro-5-tosylfuran, 2-nitro-5-tosyl-furan, ncimech_000297, 2-nitro-5-p-toluenesulfonylfuran, 2-nitro-5-p-tolylsulfonyl furan, 2-nitro-5-toluene-4-sulfonyl-furan, 2-4-methylphenyl sulfonyl-5-nitro-furan, furan, 2-4-methylphenyl sulfonyl-5-nitro
PubChem CID 394449
IUPAC Name 2-(4-methylphenyl)sulfonyl-5-nitrofuran
SMILES CC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(O2)[N+](=O)[O-]

Specifications

Quantity 10 mg
Formula Weight 267.26
Percent Purity >98%
Chemical Name or Material NSC 697923

Safety and Handling

Recommended Storage Store at +4°C
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