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NSC 87877, Tocris Bioscience™

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Quantity:
50 mg
This item is not returnable. View return policy
56990-57-9
C19H13N3O7S2
459.447
BIQBDHSYQMHHPU-CJLVFECKSA-N
8-hydroxy-7-6-sulfo-naphthalen-2-ylazo-quinoline-5-sulfonic acid, 8-hydroxy-7-6-sulfo-2-naphthyl azo-5-quinolinesulfonic acid, ncistruc1_001562, ncistruc2_001738, 8-hydroxy-7-6-sulfonaphthalen-2-yl diazenyl-quinoline-5-sulfonic acid, 8-hydroxy-7-6-sulfonaphthalen-2-yl diazenyl quinoline-5-sulfonic acid, 8-hydroxy-7-e-6-sulfo-2-naphthyl azo quinoline-5-sulfonic acid, 7e-8-oxo-7-6-sulfonaphthalen-2-yl hydrazinylidene quinoline-5-sulfonic acid
5459322
(7E)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic acid
C1=CC2=C(C(=O)C(=NNC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)O)C=C2S(=O)(=O)O)N=C1
This item is not returnable. View return policy
56990-57-9
C19H13N3O7S2
459.447
BIQBDHSYQMHHPU-CJLVFECKSA-N
8-hydroxy-7-6-sulfo-naphthalen-2-ylazo-quinoline-5-sulfonic acid, 8-hydroxy-7-6-sulfo-2-naphthyl azo-5-quinolinesulfonic acid, ncistruc1_001562, ncistruc2_001738, 8-hydroxy-7-6-sulfonaphthalen-2-yl diazenyl-quinoline-5-sulfonic acid, 8-hydroxy-7-6-sulfonaphthalen-2-yl diazenyl quinoline-5-sulfonic acid, 8-hydroxy-7-e-6-sulfo-2-naphthyl azo quinoline-5-sulfonic acid, 7e-8-oxo-7-6-sulfonaphthalen-2-yl hydrazinylidene quinoline-5-sulfonic acid
5459322
(7E)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic acid
C1=CC2=C(C(=O)C(=NNC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)O)C=C2S(=O)(=O)O)N=C1

Description

Potent inhibitor of shp2 and shp1 PTP

Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μM for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Quantity 50 mg
Formula Weight 459.45
Percent Purity >98%
Chemical Name or Material NSC 87877

Safety and Handling

Recommended Storage : Store at +4°C