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  7. NSC 95397, Tocris Bioscience™

NSC 95397, Tocris Bioscience™

Catalog No. 154710
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective Cdc25 dual specificity phosphatase inhibitor

Potent and selective irreversible inhibitor of Cdc25 dual specificity phosphatases (Ki values are 32, 96 and 40 nM for inhibition of Cdc25A, -B and -C respectively). Displays 125 - 180-fold selectivity over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. Inhibits carcinoma cell growth and blocks G2/M phase transition in vitro.

Chemical Identifiers

CAS 93718-83-3
Molecular Formula C14H14O4S2
Molecular Weight (g/mol) 310.382
InChI Key MAASHDQFQDDECQ-UHFFFAOYSA-N
Synonym 2,3-bis 2-hydroxyethylthio-1,4-naphthalenedione, 2,3-bis 2-hydroxyethylsulfanyl naphthalene-1,4-dione, 2,3-bis 2-hydroxyethyl sulfanyl naphthalene-1,4-dione, 1,4-naphthalenedione, 2,3-bis 2-hydroxyethyl thio, tocris-1547, lopac-n-1786, d0j1kh, 1, 2,3-bis 2-hydroxyethyl thio, nsc hplc, 2,3-bis 2-hydroxyethylthio naphthalene-1,4-dione
PubChem CID 262093
IUPAC Name 2,3-bis(2-hydroxyethylsulfanyl)naphthalene-1,4-dione
SMILES C1=CC=C2C(=C1)C(=O)C(=C(C2=O)SCCO)SCCO

Specifications

Quantity 10 mg
Formula Weight 310.38
Percent Purity >97%
Chemical Name or Material NSC 95397

Safety and Handling

Recommended Storage Desiccate at -20°C
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